use strict;
my $str = '<span id="3">
HELLO THERE
<span id="5">
Other stuff
<span id="6">
Other Stuff
<span id="7">
Other sutff';
my $regex = qr/([\s\S].*?)(<.+>)/mp;
my $subst = '$2';
my $result = $str =~ s/$regex/$subst/rg;
print "The result of the substitution is' $result\n";
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Perl, please visit: http://perldoc.perl.org/perlre.html