const regex = /(\G(?!^|(?:[0-9A-Za-z][^0-9A-Za-z]*){2}$)|^(?:[^0-9A-Za-z]*[0-9A-Za-z]){5})./gm;
// Alternative syntax using RegExp constructor
// const regex = new RegExp('(\\G(?!^|(?:[0-9A-Za-z][^0-9A-Za-z]*){2}$)|^(?:[^0-9A-Za-z]*[0-9A-Za-z]){5}).', 'gm')
const str = `A1../D//FASDFAS--DFASD//.F`;
const subst = `$1*`;
// The substituted value will be contained in the result variable
const result = str.replace(regex, subst);
console.log('Substitution result: ', result);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for JavaScript, please visit: https://developer.mozilla.org/en/docs/Web/JavaScript/Guide/Regular_Expressions