$re = '/([АВЕКМНОРСТУХавекмнорстухABEKMHOPCTYXabekmhopctyx]\s*\d{3}\s*[АВЕКМНОРСТУХавекмнорстухABEKMHOPCTYXabekmhopctyx]{2}\s*\d{2,3})|([АВЕКМНОРСТУХавекмнорстухABEKMHOPCTYXabekmhopctyx]{2}\s*\d{3}\s*\d{2,3})/m';
$str = '+ а222aA22
+ A222Aa22
- а222ЛЮ22
- а22аа22
+ аа22222
+ аа222 22
+ аа222 222
';
preg_match_all($re, $str, $matches, PREG_SET_ORDER, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php