$re = '/<h6 class="panel-title">\s*<i class="icon-file-music2"><\/i>(.*?)<i class=" icon-info3 text-success" data-popup="tooltip" data-html="true" title="(.*?)" data-placement="bottom"><\/i>\s*<\/h6>/s';
$str = '<div class="panel-heading">
<h6 class="panel-title"><i class="icon-file-music2"></i> TRXD - Sometimes.mp3
<i class=" icon-info3 text-success" data-popup="tooltip" data-html="true" title="<b>Uploaded on:</b><br/> 2017-11-14 06:56:54<br> <b>Downloads:</b><br/> 7" data-placement="bottom"></i>
</h6>
</div>';
preg_match_all($re, $str, $matches, PREG_SET_ORDER, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php