use strict;
my $str = 'parent:
A:
name: foo
value: x.y.z # check=something
# value: "yay" # check=nothing
B:
name: bar
value: p.q.r # check=something
# value: "yay" # check=nothing';
my $regex = qr/(^\s*)#\s(.*)$/mp;
my $subst = '$1$2';
my $result = $str =~ s/$regex/$subst/rg;
print "The result of the substitution is' $result\n";
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Perl, please visit: http://perldoc.perl.org/perlre.html