$re = '/Teacher_name:[\w\s]+,\s*Remarks:[\w\s]+,\s*/i';
$str = 'Subject_name: English, Teacher_name: John Doe, Remarks: some comment, Overall_marks:87,
Subject_name: Mathematics, Teacher_name: Doe John, Remarks: some comment, Overall_marks:75,
Subject_name: Science, Teacher_name: JD, Remarks: some comment, Overall_marks:80,';
$subst = "";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php