const regex = /-?0+\.(0)+\b|\.0+\b|\b0+(?=\.\d*[1-9])|\b0+(?=[1-9]\d*\.)|(\.\d*?)0+\b/g;
// Alternative syntax using RegExp constructor
// const regex = new RegExp('-?0+\\.(0)+\\b|\\.0+\\b|\\b0+(?=\\.\\d*[1-9])|\\b0+(?=[1-9]\\d*\\.)|(\\.\\d*?)0+\\b', 'g')
const str = `00.00
00002.0
3.00
-4.0
0.00
-0.00
0.03
2.01
0.001
-0.03
101
0.001
-0.03
.50
00.00
11.000000`;
const subst = `$1$2`;
// The substituted value will be contained in the result variable
const result = str.replace(regex, subst);
console.log('Substitution result: ', result);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for JavaScript, please visit: https://developer.mozilla.org/en/docs/Web/JavaScript/Guide/Regular_Expressions