const regex = /^(?!MsgBox\().*(*SKIP)(*F)|(?:(?:.{1,70}|.{71,140}|.{141,210}|.{211,280})|\G(?!^))\S+\K\h(?=.{25,}$)/gm;
// Alternative syntax using RegExp constructor
// const regex = new RegExp('^(?!MsgBox\\().*(*SKIP)(*F)|(?:(?:.{1,70}|.{71,140}|.{141,210}|.{211,280})|\\G(?!^))\\S+\\K\\h(?=.{25,}$)', 'gm')
const str = `'Some looooooong comment Lorem ipsum dolor sit amet, consectetur adipiscing
'elit. Ut a volutpat dolor. In risus odio, pharetra a arcu in, efficitur
'ornare lectus. Maecenas non aliquet leo. Praesent luctus blandit
'magna, et sagittis ex porta et.
MsgBox("Some text in MsgBox. Donec vulputate eros ac nulla hendrerit auctor. In hac habitasse platea dictumst. Proin fermentum augue elit, eget consequat massa mattis et. Integer semper imperdiet diam sit amet malesuada.", 64, "Title of MsgBox")
'Another comment now with link to doc.
'https://example.com/?bs64=SWYgeW91IGFyZSBzbWFydCBlbm91Z2ggdG8gZGVjb2RlLCB5b3UgbXVzdCBkZWZpbml0ZWx5IHdhdGNoIHRoaXM6IGh0dHBzOi8vd3d3LnlvdXR1YmUuY29tL3dhdGNoP3Y9b0hnNVNKWVJIQTA=`;
const subst = ` " _\n & "`;
// The substituted value will be contained in the result variable
const result = str.replace(regex, subst);
console.log('Substitution result: ', result);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for JavaScript, please visit: https://developer.mozilla.org/en/docs/Web/JavaScript/Guide/Regular_Expressions