$re = '/^\w+(?<!_min)\.(jpg|gif)/m';
$str = 'desc_125f.jpg -> matched,
desc#_56.jpg -> not matched (contains #),
bla_bla.gif -> matched,
bla_bla.png -> not matched (extension is png),
desc_125f_min.jpg -> not matched (contains _min between a filename and an extension),
desc_min256.gif';
preg_match_all($re, $str, $matches, PREG_SET_ORDER, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php