$re = '/([0-9A-F])([0-9A-F])([0-9A-F])([0-9A-F])([0-9A-F])([0-9A-F])([0-9A-F])([0-9A-F])\-([0-9A-F])([0-9A-F])([0-9A-F])([0-9A-F])\-4([0-9A-F])([0-9A-F])([0-9A-F])\-([0-9A-F])([0-9A-F])([0-9A-F])([0-9A-F])\-([0-9A-F])([0-9A-F])([0-9A-F])([0-9A-F])([0-9A-F])([0-9A-F])([0-9A-F])([0-9A-F])([0-9A-F])([0-9A-F])([0-9A-F])([0-9A-F])/mi';
$str = 'D01A42F5-FD89-4c8f-8065-726AD4363411';
$subst = "$31$1$30$2$29$3$28$4-$27$5$26$6-4$25$7$24-$8$23$9$22-$10$21$11$20$12$19$13$18$14$17$15$16";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php