$re = '/(?:http?:\/\/|https?:\/\/)?(?:www\.)?stackoverflow\.com\/(?:\/*)([\w\-\.\/]*)/m';
$str = 'http://stackoverflow.com/cv/razvan-ciocanel
http://stackoverflow.com/users/759476/r%C4%83zvan-cioc%C4%83nel?tab=profile';
$subst = "";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php