const regex = /(?!^)(?<!\d[.A-Z])(?<!\d[A-Z]\.)\b(?=\d+(?:[a-zA-Z]|\.)\s+\p{Lu})/g;
// Alternative syntax using RegExp constructor
// const regex = new RegExp('(?!^)(?<!\\d[.A-Z])(?<!\\d[A-Z]\\.)\\b(?=\\d+(?:[a-zA-Z]|\\.)\\s+\\p{Lu})', 'g')
const str = `5. SCOPE This document outlines what to do in case of emergency landing (ignore for non-emergency landings) on tarmac. 6. WHEELS Never land on tarmac. Unless you have lowered the plane wheel mechanism. 6.1 Lower the wheel mechanism using the 2 Switches labelled 'wheel mechanism'. 7A WARNING 7A.1 Do not forget to warn passengers.
`;
const subst = `\n-----------\n`;
// The substituted value will be contained in the result variable
const result = str.replace(regex, subst);
console.log('Substitution result: ', result);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for JavaScript, please visit: https://developer.mozilla.org/en/docs/Web/JavaScript/Guide/Regular_Expressions