const regex = /((?:bs )?(?:en )?(?:np )?is[o0]\s+[-\d]+:)(.+:)?(\d{4}(?:\(e\))?)/img;
// Alternative syntax using RegExp constructor
// const regex = new RegExp('((?:bs )?(?:en )?(?:np )?is[o0]\\s+[-\\d]+:)(.+:)?(\\d{4}(?:\\(e\\))?)', 'img')
const str = `ISO 11784:1996/Amd.2:2010(E)
ISO 11784:2010(E)
ISO 11784:2010
ISO 11784-2-3-4:1996/Amd.2:2010(E)
ISO 11784-2-8-7:2010(E)
ISO 11784-5-120-78949-56-789:2010
BS EN ISO 11784:1996/Amd.2:2010(E)
EN ISO 11784:2010(E)
IS0 11784:2010
EN NP IS0 11784-2-3-4:1996/Amd.2:2010(E)
BS IS0 11784-2-8-7:2010(E)
EN NP ISO 11784-5-120-78949-56-789:2010
`;
const subst = `$1$3`;
// The substituted value will be contained in the result variable
const result = str.replace(regex, subst);
console.log('Substitution result: ', result);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for JavaScript, please visit: https://developer.mozilla.org/en/docs/Web/JavaScript/Guide/Regular_Expressions