$re = '/(.+?)(\s)([A-Z].[A-Z].,)(\s)(.+?)(\s)([A-Z].[A-Z].,)(\s)(.+?)(\s)([A-Z].[A-Z].)(\s)(and)(\s)(.+?)(\s)([A-Z].[A-Z].)/';
$str = 'Blois J.L., Zarnetske P.L., Fitzpatrick M.C. and Finnegan S.B.';
$subst = "";
$result = preg_replace($re, $subst, $str, 1);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php