use strict;
my $str = '/friends?guest=1&event=chill_out&submit=2
/friends/?more_params
/friend/?more_params
/friend?more_params';
my $regex = qr/\/(.*(?<!friends)(?<!friends\/))\?.*$/mp;
my $subst = '$1';
my $result = $str =~ s/$regex/$subst/rg;
print "The result of the substitution is' $result\n";
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Perl, please visit: http://perldoc.perl.org/perlre.html