$re = '/^\s*([^\s*]|\*\s*[^\sG]|\*\sG[^e]|\*\sGe[^n]|\*\sGen[^e]|\*\sGene[^r]|\*\sGener[^a]|\*\sGenera[^t]|\*\sGenerat[^e]|\*\sGenerate[^d]).*/m';
$str = ' * Generated at 2018-11-21
* General
* Green
* This line is important! Although it starts with a *
* This line should be important, but there it contains a "Generated at"...
#define foo
# define bar
return 0;';
preg_match_all($re, $str, $matches, PREG_SET_ORDER, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php