# If you'd like to omit non-matching lines from the result; add ';d' to the end of the expression.
sed -E 's/(?<=,|^)[0.+-]+(?=0(?:,|$))|\.0+\b|\b0+(?=\.)//g;t' <<< "2.0,3.00,-4.0,0.00,-0.00,0.03,2.01,0.001,-0.03,101"
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for SED, please visit: https://www.gnu.org/software/sed/manual/html_node/The-_0022s_0022-Command.html