$re = '/http(?:s)?\://boards\.4chan\.org/([a-z]*)/thread/([0-9]*)(?:\#[0-9a-z]*)?/';
$str = 'https://boards.4chan.org/mlp/thread/5
http://boards.4chan.org/b/thread/570277846
https://boards.4chan.org/mlp/thread/19865655#q19865655
https://boards.4chan.org/mlp/thread/19775771
https://boards.4chan.org/co/thread/65737750#q65737750';
$subst = "Thread $2 on mlp";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php