$re = '/(The reason for this is\s*:\s*)(\S*(?:\s(?!\s*Kind regards)\S+)*)(\s*Kind regards)/';
$str = 'The reason for this is: 111111111
2222
3333
ddddddddd
Kind regards.';
preg_match($re, $str, $matches, PREG_OFFSET_CAPTURE, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php