use strict;
my $str = '1H|\\^&|||ARCHITECT^8.10^F3453010030^H1P1O1R1C1Q1L1|||Admin||||P|1|20150511083525
1D';
my $regex = qr/\|*Admin\|*/imp;
my $subst = '|';
my $result = $str =~ s/$regex/$subst/rg;
print "The result of the substitution is' $result\n";
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Perl, please visit: http://perldoc.perl.org/perlre.html