$re = '/(?=^[A-Z]{3}[0-9]{2}[A-Z0-9]{8}[0-9]{2}$)
helloJellofellow
600566604081/';
$str = 'hel01Jeloofel10
';
$subst = "600566604081";
$result = preg_replace($re, $subst, $str, 1);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php