$re = '/(?<=([aui]))[wy](?=\1)|(?<=i)[wy](?=u)/';
$str = 'asdawasda
asdayasda
asdiwisda
asdiyisda
asduwusda
asduyusda
asdawisda
asdawusda
asdayisda
asdayusda
asdiwasda
asdiwusda
asdiyasda
asdiyusda
asduwasda
asduwisda
asduyasda
asduyisda
ramiyun
da9iwun';
$subst = "";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php