$re = '/(Failed to handle request ).+( on subject.*)/';
$str = 'Failed to handle request 0[null->null s:0 w:0.0 a: 0.0 S:0 t: 24543060 s(NA) (0 0)] on subject RealTimeUpdate
Failed to handle request blablabla on subject RealTimeUpdate
Failed to handle request test0120120120 on subject RealTimeUpdate';
preg_match_all($re, $str, $matches, PREG_SET_ORDER, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php