$re = '/(\{\"TimePeriod\":){1}.+?(false\}){1}/m';
$str = '{"TimePeriod": {"Start": "2017-03-01", "End": "2017-04-01"}, "Total": {"UnblendedCost": {"Amount": "2942.25119998", "Unit": "USD"}, "UsageQuantity": {"Amount": "20835", "Unit": "Hrs"}}, "Groups": [], "Estimated": false},{"TimePeriod": {"Start": "2017-04-01", "End": "2017-05-01"}, "Total": {"UnblendedCost": {"Amount": "2982.62609983", "Unit": "USD"}, "UsageQuantity": {"Amount": "21049", "Unit": "Hrs"}}, "Groups": [], "Estimated": false},{"TimePeriod": {"Start": "2017-05-01", "End": "2017-06-01"}, "Total": {"UnblendedCost": {"Amount": "1399.04829988", "Unit": "USD"}, "UsageQuantity": {"Amount": "23010", "Unit": "Hrs"}}, "Groups": [], "Estimated": false},{"TimePeriod": {"Start": "2017-06-01", "End": "2017-07-01"}, "Total": {"UnblendedCost": {"Amount": "962.47549987", "Unit": "USD"}, "UsageQuantity": {"Amount": "20049", "Unit": "Hrs"}}, "Groups": [], "Estimated": false}
';
$subst = "";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php