re = /(<a .*?)(href="|\')(http:\/\/oceanexplorer.noaa.gov\/redirectimage.php\?url=|\/redirectimage.php\?url=|\/redirectimage.php\?url=)([.\s\S]*?)(<\/a>)/
str = 'g_ImageTable[g_imax++] = new Array ("gallery/600/1.jpg", "The inflatable baby pool used for the phytoplankton experiment. <em>Image courtesy of 2009 RUSALCA Expedition, RAS-NOAA.</em><br /><br /><!--strong><a href=\'/redirectimage.php?url=http://oceanexplorer.noaa.gov/explorations/09bioluminescence/background/hires/bamboo_coral_hires.jpg\' title=\'Download high-resolution image\' target=\'window_name\'>Download high-resolution image (jpg, 547 KB)</a></strong-->");
'
subst = '\\1\\2\\4 <img src="/siteart/newwindow.png" width="10" height="11" alt="exit icon" title="exit icon"/>\\5'
result = str.gsub(re, subst)
# Print the result of the substitution
puts result
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Ruby, please visit: http://ruby-doc.org/core-2.2.0/Regexp.html