import Foundation
let pattern = ##"(,)?(\d)(\d*)(?=(?=,|:).*?~.*?;0*\2\3_(.)(.{3}))|(,)(\d)(\d{3})(?=(?=,|:))|(:)(\d)|(#)(?=\d)(?=.*(,))"##
let regex = try! NSRegularExpression(pattern: pattern)
let testString = ##"#:10100010~;0101_1000;0110_1001;0111_1010;1000_1011;1001_1100;1010_1101;1011_1110;1100_1111,~0000_00001_10010_20011_30100_40101_50110_60111_71000_81001_9"##
let stringRange = NSRange(location: 0, length: testString.utf16.count)
let substitutionString = #"$4$7$1$6$5$8$10$9$11$12"#
let result = regex.stringByReplacingMatches(in: testString, range: stringRange, withTemplate: substitutionString)
print(result)
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Swift 5.2, please visit: https://developer.apple.com/documentation/foundation/nsregularexpression