$re = '/(?i)(http|https|ftp|ftps)://\S*\.(exe|hta|htr|scr)(\S*|\b|$)/m';
$str = 'https://oedginnrrl.execute-api.us-east-1.amazonaws.com/v1/readstatus?MailingID=112129934&Email=jn47w%40nih.gov"
https://oedginnrrl.execute-api.us-east-1.amazonaws.com/v1/readstatus?MailingID=112131410&Email=james.king%40nih.gov"
http://list.nih.gov/cgi-bin/wa.exe?SUBED1=PHS-AD-PHARMACISTS&A=1
https://oedginnrrl.execute-api.us-east-1.amazonaws.com/v1/readstatus?MailingID=112130096&Email=jerry.suls%40nih.gov"
https://web.streamlinevrs.com/pmt_common/d_images/email_186198972.script
http://www.scripps.edu/>
https://oedginnrrl.execute-api.us-east-1.amazonaws.com/v1/readstatus?MailingID=112129882&Email=james.welch%40nih.gov"
';
preg_match_all($re, $str, $matches, PREG_SET_ORDER, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php