$re = '/(?<![Ii]s)a{2,}/m';
$str = 'Lorem ipsum dolor sit aamet, consectetur aaadipiscing elit, Isaac sed do eiusmod tempor incididunt ut labore et dolore magnaaa aliqua. Ut enim ad minim veniaaaam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat, isaac. Duis aaaaaaute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nullaaaa pariatur. Isaac excepteur sint occaecat cupidatat non proident, sunt in culpaa qui officia deserunt mollit anim id est laborum.';
preg_match_all($re, $str, $matches, PREG_SET_ORDER, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php