use strict;
my $str = 'los angeles, ca';
my $regex = qr/^.+? ?, ?(A[LKSZRAP]|C[AOT]|D[EC]|F[LM]|G[AU]|HI|I[ADL N]|K[SY]|LA|M[ADEHINOPST]|N[CDEHJMVY]|O[HKR]|P[ARW]|RI|S[CD] |T[NX]|UT|V[AIT]|W[AIVY])$/ip;
my $subst = '';
my $result = $str =~ s/$regex/$subst/r;
print "The result of the substitution is' $result\n";
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Perl, please visit: http://perldoc.perl.org/perlre.html