use strict;
my $str = 'as234-H344423-dfX|dfer XXYUyu werg|1g|z4|sweDSgIKU|2017-SS0|123.45|YTf
as234-H3wer23-dZ|df3r Xa12yu wg|a1|2|sweDSgIKU|2017-SS0|123.45|YTf
as234-HJ123-HG|dfdf KHT werg|XXL|s45dtgIKU|2017-SS0|123.45|asUJY';
my $regex = qr/^((?:[^|]+\|){2})([^|]+\|[^|]{,2}(?=\|))/mp;
my $subst = '\\1"\\2"';
my $result = $str =~ s/$regex/$subst/rg;
print "The result of the substitution is' $result\n";
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Perl, please visit: http://perldoc.perl.org/perlre.html