$re = '/\!?empty\(([^)]+)\)/m';
$str = '!empty($act_s[10])
empty($act_s[10])
empty($act_s[10])
empty($Znachenie)
empty($Znachenie[$luboy_Dlinny])';
$subst = "${1}==\"\"";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php