$re = '/{{\s*([^{}]+\S)\s*}}/m';
$str = 'Hello there, {{name}}
Hello there, {{ name }}
Hello there, {{ name }}';
$subst = "General Kenobi";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php