use strict;
my $str = 'bst.instance.red.port="5555"
bst.instance.red.dpi="240"
bst.instance.red.fb_height="900"
bst.instance.red.fb_width="1600"
bst.instance.red.first_boot="0"
bst.instance.redb.port="2000"
bst.instance.redb.dpi="120"
bst.instance.redb.fb_height="300"
bst.instance.redb.fb_width="800"
bst.instance.redb.first_boot="0"
bst.instance.redc.port="2000"
bst.instance.redc.dpi="120"
bst.instance.redc.fb_height="300"
bst.instance.redc.fb_width="800"
bst.instance.redc.first_boot="0"';
my $regex = qr/\b(?:(port)|(dpi)|(fb_height)|(fb_width))="\K\d+/p;
my $subst = '${1:+111}${2:+222}${3:+333}${4:+444}';
my $result = $str =~ s/$regex/$subst/rg;
print "The result of the substitution is' $result\n";
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Perl, please visit: http://perldoc.perl.org/perlre.html