$re = '/(?:^\h*C\h+|\G(?!^))\h*,*\h*\K\d+/im';
$str = '1,2 , 4,5
d 12456, 9890
C 1,13,7,2,55';
preg_match_all($re, $str, $matches, PREG_SET_ORDER, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php