#include <MsgBoxConstants.au3> ; to declare the Constants of MsgBox
Local $sRegex = "(?m)\b\d+(?:\.\d+)?\b(*SKIP)(*F)|\d"
Local $sString = "my text contains of the 33109 following values RT3123SO55 and also with certain numbers godwil_5708 and 323stwe and 8y9yc2 456453"
Local $sSubst = "*"
Local $sResult = StringRegExpReplace($sString, $sRegex, $sSubst)
MsgBox($MB_SYSTEMMODAL, "Result", $sResult)
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for AutoIt, please visit: https://www.autoitscript.com/autoit3/docs/functions/StringRegExp.htm