const regex = new RegExp('-|:', 'g')
const str = `GB,16,19,255,1,26:40,19,13,4,2,6-12,0-1,255,57,4.5,80,21,3.8,175,23-33,4.9,3,14,1,4,38.3,8,65,1,0 Sea,36,25,398,1,33:20,25,8,13,4,4-11,1-1,398,66,6.0,207,37,5.6,191,19-28,6.6,1,0,0,2,33.0,4,69,2,1`;
const subst = `,`;
// The substituted value will be contained in the result variable
const result = str.replace(regex, subst);
console.log('Substitution result: ', result);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for JavaScript, please visit: https://developer.mozilla.org/en/docs/Web/JavaScript/Guide/Regular_Expressions