const regex = /(?<=:\s).*/gm;
// Alternative syntax using RegExp constructor
// const regex = new RegExp('(?<=:\\s).*', 'gm')
const str = `Turning on API signature validation for service : PGL
Turning off API signature validation for service : PLATFORM
Turning off API signature validation for service : WEBWORKS
Turning on API signature validation for service : TIMER_SINK
Turning on API signature validation for service : MESSAGING
Turning on API signature validation for service : EMAIL
Turning off API signature validation for service : USER_SECURITY
Initializing MDM for :USER_SECURITY
<MDM/>`;
const subst = `$1`;
// The substituted value will be contained in the result variable
const result = str.replace(regex, subst);
console.log('Substitution result: ', result);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for JavaScript, please visit: https://developer.mozilla.org/en/docs/Web/JavaScript/Guide/Regular_Expressions