$re = '/::\K\s+|\s*\n(?=[^:]*(\n|$))\s*/';
$str = 'dn: CN=Gast,CN=Users,DC=question,DC=local
changetype: add
objectClass: top
objectClass: person
objectClass: organizationalPerson
objectClass: user
cn: Gast
description::
Vm9yZGVmaW5pZXJ0ZXMgS29udG8gZsO8ciBHYXN0enVncmlmZiBhdWYgZGVuIENvbXB1dGVyIGJ6dy
4gZGllIERvbcOkbmU=
name: Gast
sAMAccountName: Gast
unicodePwd::IgA2AEcATQBNAHQANwBoADcAIgA=
userAccountControl:512';
$subst = "";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php