#include <MsgBoxConstants.au3> ; to declare the Constants of MsgBox
Local $sRegex = "(?i)(^|\s)(?!\b(?:basic|studio|asp|v[bs]|c\#)\.net)(\w+)(?:\.co\.[a-z]{2}|\.[a-z]{2,6})\b"
Local $sString = "site.org asp.net dsgsvgs somedomain.com sdbbdsb vb.net otherdomain.org vs.net wax.museum somesite.net vb.net micro.co.uk sdbsdbssd asp.co.uk visualbasic.co.hk ASP.net visualstudio.co.jp ddddddd visualbasic.net visual basic.net visual studio.net uuu. www.com"
Local $sSubst = "\1\2"
Local $sResult = StringRegExpReplace($sString, $sRegex, $sSubst)
MsgBox($MB_SYSTEMMODAL, "Result", $sResult)
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for AutoIt, please visit: https://www.autoitscript.com/autoit3/docs/functions/StringRegExp.htm