$re = '/(?:FAO=|\G,)\K(\d+)/m';
$str = 'chr1 11189845 COSM462604;COSM893813 G C,T 158.16 PASS AF=0,0;AO=0,0;DP=1201;FAO=0,0;FDP=1201;FR=.;
chr1 11190804 COSM180789 C T 134.06 PASS AF=0;AO=0;DP=1016;FAO=0;FDP=1018;FR=.;FRO=1018;
';
preg_match_all($re, $str, $matches, PREG_SET_ORDER, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php