const regex = /(#.+?#)([^#]+)(#.*)/gm;
// Alternative syntax using RegExp constructor
// const regex = new RegExp('(#.+?#)([^#]+)(#.*)', 'gm')
const str = `#4 MyApp\\Framework\\DB\\Adapter\\Pdo\\Mysql->_query('SELECT \`store_we...', array()) called at [vendor/myapp/framework/DB/Adapter/Pdo/Mysql.php:621]
#5 MyApp\\Framework\\DB\\Adapter\\Pdo\\Mysql->query(MyApp\\Framework\\DB\\Select#b8e969b2c2d6#, array()) called at [vendor/myapp/zendframework1/library/Zend/Db/Adapter/Abstract.php:737]
#6 Zend_Db_Adapter_Abstract->fetchAll(MyApp\\Framework\\DB\\Select#b8e969b2c2d6#) called at [vendor/myapp/module-store/App/Config/Source/RuntimeConfigSource.php:87]`;
const subst = `\1StaticText\3`;
// The substituted value will be contained in the result variable
const result = str.replace(regex, subst);
console.log('Substitution result: ', result);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for JavaScript, please visit: https://developer.mozilla.org/en/docs/Web/JavaScript/Guide/Regular_Expressions