$re = '/"0+/m';
$str = 'original_ref_list = ["005a004",
"018b003",
"007a029",
"105a015",
"0000000",]';
$subst = "\"";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php