use strict;
my $str = 'Please find the presentations:
href="/Portals/12/Documents/GE-Project/Amalty-WS/Joanna_POT Pb paint health econ env_RUS.pdf">Presentation 1';
my $regex = qr~(?:\G(?!^)|/Amalty-WS/)[^"\s]*\K\s(?=[^"]*")~mp;
my $subst = '_';
my $result = $str =~ s~$regex~$subst~rg;
print "The result of the substitution is' $result\n";
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Perl, please visit: http://perldoc.perl.org/perlre.html