$re = '/\s*\d+\s*(?:units?|times?(?:\s+(?:a|per)\s+|\s*/\s*)(?:d(?:ay)?|w(?:ee)?k|month|y(?:ea)?r?))/m';
$str = 'inJECTable 1234 Eprex DOSE 4000 units on NONd
department 6789 DOSE 8000 units on DIALYSIS days - IV Interm\',
inJECTable 4321 Eprex DOSE - 3 times/wk on NONdialysis day\',
insulin MixTARD 30/70 - inJECTable 46 units\',
insulin ISOPHANE -- InsulaTARD Vial - inJECTable 56 units SC SubCutaneous\',
1-alfacalcidol DOSE 1 mcg - 3 times a week - IV Intermittent\',
jevity liquid - FEEDS PO Jevity - 237 mL - 1 times per day\',
1-alfacalcidol DOSE 1 mcg - 3 times per week - IV Intermittent\',
1-supported DOSE 1 mcg - 1 time/day - IV Intermittent\',
1-testpackage DOSE 1 mcg - 1 time a day - IV Intermittent
///3 times a day, 3 time/wk, 3 times per day, 3 times a month, 3 times/month';
$subst = "";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php