use strict;
my $str = 'SAD; Happy; ING:train coca
SAD; Happy; ING(train coca
SAD, Happy, ING[train coca
';
my $regex = qr/(?<=[;,])\s+[A-Z]+[:([]/mp;
my $subst = ' ';
my $result = $str =~ s/$regex/$subst/rg;
print "The result of the substitution is' $result\n";
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Perl, please visit: http://perldoc.perl.org/perlre.html