#include <MsgBoxConstants.au3> ; to declare the Constants of MsgBox
Local $sRegex = "(?<=,|^)(?:[0.+-]+(?=0(?:,|\.\B|$))|0+(?=[1-9]))|\.0+\b|\b0+(?=\d*\.\b)|\.\B|(?<=[1-9])0+(?=,|$)"
Local $sString = "2.0,3.00,-4.0,0.00,-0.00,0.03,2.01,0.001,-0.03,101,-00.,0.,01,1.10,000.,.000,0.000,-004.04"
Local $sSubst = ""
Local $sResult = StringRegExpReplace($sString, $sRegex, $sSubst)
MsgBox($MB_SYSTEMMODAL, "Result", $sResult)
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for AutoIt, please visit: https://www.autoitscript.com/autoit3/docs/functions/StringRegExp.htm