$re = '/\s+(?=(?:(?:20)?[01]?[0-9])-(?:1[0-2]|0?[0-9])-(?:[0-2]?[0-9]|3[01]))/m';
$str = '2018-03-14 06:08:18, he went on 2018-03-15 06:08:18, lets play';
$subst = "\n";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php