const regex = /(<label(?!.*preferredMaxLayoutWidth).*numberOfLines.*>)/g;
// Alternative syntax using RegExp constructor
// const regex = new RegExp('(<label(?!.*preferredMaxLayoutWidth).*numberOfLines.*>)', 'g')
const str = `
<label opaque="NO" userInteractionEnabled="NO" tag="5" contentMode="left" horizontalHuggingPriority="251" verticalHuggingPriority="251" text="Label" lineBreakMode="tailTruncation"="4" baselineAdjustment="alignBaselines" adjustsFontSizeToFit="NO" translatesAutoresizingMaskIntoConstraints="NO" id="fgY-Rp-veR">
<rect key="frame" x="6" y="40" width="288" height="60"/>
<animations/>
<constraints>
<constraint firstAttribute="height" constant="60" id="g3c-hD-Hf9"/>
</constraints>
<fontDescription key="fontDescription" type="system" pointSize="12"/>
<color key="textColor" red="0.0" green="0.0" blue="0.0" alpha="1" colorSpace="calibratedRGB"/>
<nil key="highlightedColor"/>
</label>
<label opaque="NO" userInteractionEnabled="NO" numberOfLines="4" tag="10" contentMode="left" text="feedback" lineBreakMode="tailTruncation" numberOfLines="4" baselineAdjustment="alignBaselines" adjustsFontSizeToFit="NO" translatesAutoresizingMaskIntoConstraints="NO" id="M98-QE-PMx">
<rect key="frame" x="7" y="227" width="287" height="70"/>
<animations/>
<constraints>
<constraint firstAttribute="height" constant="70" id="uPb-iM-7XM"/>
</constraints>
<fontDescription key="fontDescription" type="system" pointSize="14"/>
<color key="textColor" red="0.058823529409999999" green="0.51372549020000002" blue="0.94901960780000005" alpha="1" colorSpace="calibratedRGB"/>
<nil key="highlightedColor"/>
</label>`;
const subst = ``;
// The substituted value will be contained in the result variable
const result = str.replace(regex, subst);
console.log('Substitution result: ', result);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for JavaScript, please visit: https://developer.mozilla.org/en/docs/Web/JavaScript/Guide/Regular_Expressions