$re = '/\[INFO\] \[(\S+):\d+\S+\] Authentication failed with user: \'(\S*)\'.$/';
$str = '2015-12-02 23:17:35.845 [INFO] [IP.ADD.RE.SS:50364:HTTP2-7] Authentication failed with user: \'username\'.';
preg_match($re, $str, $matches, PREG_OFFSET_CAPTURE, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php