$re = '/(?s)(?:(?!(?<!\w)\w(?!\w)).)+/';
$str = 'I need to use regular expressions to draw all the individual letters from the entire sentence, and the result must be in only one group, it can not be a separate group. E.g:
This is an example sentence in which I have two letters: ';
$subst = "\n";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php